Beta‐carotene and vitamin E both fulfill all the criteria for suitable chemopreventive agents; several lines of evidence point toward preventive roles for them in oral cancer. In numerous epidemiologic studies, low intake of beta‐carotene has been associated with higher cancer risk.
The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. [No authors listed] BACKGROUND. Epidemiologic evidence indicates that diets high in carotenoid-rich fruits and vegetables, as well as high serum levels of vitamin E (alpha-tocopherol) and beta carotene, are associated with a reduced risk of lung cancer. METHODS. We
O2∙. DNA-skador. A, C, E vitaminer. Beta-karotene Alpha-Tocopherol/Beta-Carotene Cancer Prevention Study (ATBC) N. Engl. J. Med. 1994.
According to the American Cancer Society, this nutrient may prevent certain cancers by enhancing the white blood cells in your immune system. White blood cells work to block cell-damaging free radicals. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study conducted in southwestern Finland has been an integral cohort research resource for NCI for nearly three decades. METHODS: Our study included 29,133 Finnish male smokers followed prospectively in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study (1985-2005). Lung cancers were identified through linkage with the Finnish Cancer Registry, and hospital-treated tuberculosis cases were ascertained from the National Hospital Discharge Register. The con‐clusion that major public health benefits could be achieved by increasing consumption of carotenoid‐ rich fruits and vegetables still appears to stand; however, the pharmacological use of supplemental beta‐carotene for the prevention of cardiovascular disease and lung cancer, particularly in smokers, can no longer be recommended.—Mayne, S. T. Betacarotene, carotenoids, and Abstract. Lack of toxicity and easy availability make beta-carotene and vitamin E excellent agents to test for cancer preventive activity.
The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study was a randomized, double-blind, placebo-controlled primary-prevention trial undertaken to determine whether supplementation with alpha
In numerous epidemiologic studies, low intake of beta‐carotene has been associated with higher cancer risk. 1999-11-22 The ATBC Study was a double-blind, placebo-controlled, 2 ×2 factorial-design primary prevention trial that tested whether alpha-tocopherol or beta-carotene supplementation reduced cancer incidence in Finnish male smokers (21).
1994-10-07
av A Ledin — emot organismer (cancer, mutagena effekter, reprodukt- ionsskador b Data från ett bas batteri av standardiserade sötvatten toxicitets tester (fisk, kräftdjur, alger). Den förväntade OSPAR (2003). Commission for the protection of the Marine Environment of the North-East. E160a alpha-, beta-, gamma-carotene.
1996; 334:1150-5. Albanes D, Heinonen OP, Taylor PR, et al. Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and
The Alpha-Tocopherol Beta Carotene Cancer Prevention Study Group The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med. 1994; 330 : 1029-1035
ATBC: The Alpha-Tocopherol, Beta-Carotene (ATBC) Cancer Prevention Study Group.
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The effect of Hudcancer är som tidigare nämnts den cancerform som ökar mest i vårt land. Det är även klarlagt att The Alpha-Tocopherol, Beta Carotene Cancer Prevention. av T Woodhill — 13 The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study Group. Effects of beta- carotene supplements on cancer prevention: Plasma carotenoids (- and -carotene, lycopene, -cryptoxanthin, canthaxanthin, Fruits and vegetables may play a role in the prevention of pancreatic cancer, av MG Sajilata · 2008 · Citerat av 211 — spectrum of zeaxanthin, a derivative of β-carotene, resembles Cancer.
The most scientifically rigorous method for testing the hypothesis that beta-carotene has chemopreventive properties is with intervention trials, several of
Similarly, the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) trial was stopped early after it was found that in male smokers, high-dose β-carotene supplements increased lung cancer risk (RR= 1.18, 95% CI= 1.03-1.36).
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Bilaga B. Primärpreventiva randomiserade studier riktade mot en eller flera riskfaktorer E and beta carotene on the incidence of lung cancer and other can-.
Vaai^Y prevention of porcine Escherichia coli enterotoxaemia. Vet. Carotenes in plants. av A Ledin — emot organismer (cancer, mutagena effekter, reprodukt- ionsskador b Data från ett bas batteri av standardiserade sötvatten toxicitets tester (fisk, kräftdjur, alger).
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"The Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study (1985-1993) recruited 29,133 Finnish male cigarette smokers, finding that vitamin E
Later: no effect on risk of dying from gastric cancer. Alpha-Tocopherol/Beta-Carotene Cancer Prevention Study (ATBC), Finland (8–12) Alpha-tocopherol (50 mg per day) and/or beta-carotene (20 mg per day) supplements for 5 to 8 years: Middle-aged male smokers: Initial: increased incidence of lung cancer for those who took beta-carotene supplements Previous studies have suggested that higher intakes of vitamin E (alpha-tocopherol) and beta carotene may be associated with a reduced risk of lung cancer. In particular, epidemiologic studies ALPHA-TOCOPHEROL, beta carotene cancer prevention. study group. The effect of vitamin E and beta carotene.